Pygopus Maintains Heart Function in Aging Drosophila Independently of Canonical Wnt Signaling
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چکیده
منابع مشابه
Pygopus maintains heart function in aging Drosophila independently of canonical Wnt signaling.
BACKGROUND Heart function declines with age, but the genetic factors underlying such deterioration are largely unknown. Wnt signaling is known to play a role in heart development, but it has not been shown to be important in adult heart function. We have investigated the nuclear adapter protein encoded by pygopus (pygo), which mediates canonical Wnt signaling, for roles in aging-related cardiac...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Genetics
سال: 2013
ISSN: 1942-325X,1942-3268
DOI: 10.1161/circgenetics.113.000253